Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28629417 | 0.93 | NAMPT (0.58) | NAMPTROCK2ROCK1IMPDH2ADORA3 | |
| SCHEMBL30943224 | 0.78 | NAMPT (0.84) | NAMPTROCK2ROCK1IMPDH2 | |
| SCHEMBL24042554 | 0.78 | NAMPT (0.84) | NAMPTROCK2ROCK1IMPDH2 | |
| SCHEMBL30943229 | 0.76 | NAMPT (0.75) | NAMPTROCK2ROCK1IMPDH2 | |
| SCHEMBL23320533 | 0.76 | NAMPT (0.75) | NAMPTROCK2ROCK1IMPDH2 | |
| SCHEMBL23320444 | 0.71 | NAMPT (1.00) | NAMPT | |
| SCHEMBL23320352 | 0.70 | NAMPT (0.42) | NAMPTROCK2ROCK1ADORA3ADORA1 | |
| SCHEMBL24042588 | 0.69 | NAMPT (0.77) | NAMPTROCK2ROCK1 | |
| SCHEMBL23320389 | 0.68 | NAMPT (1.00) | NAMPTROCK2ROCK1IMPDH2ADORA3 | |
| SCHEMBL23320379 | 0.65 | NAMPT (0.41) | NAMPTROCK2ROCK1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |