Formamide

Formamide

SCHEMBL28629462

Cc1nnc2ccccc2c1C.NC=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.46
ERN1 O75460 1/20 0.40
HTT P42858 2/20 0.39
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 3/20 0.39
CYP1A2 P05177 3/20 0.39
HPGD P15428 2/20 0.39
NUDT1 P36639 1/20 0.39
LCK P06239 1/20 0.39
MAP2K3 P46734 1/20 0.39
MAP2K6 P52564 1/20 0.39
BTK Q06187 1/20 0.39
MAP3K19 Q56UN5 1/20 0.39
NEK10 Q6ZWH5 1/20 0.39
PDE10A Q9Y233 1/20 0.39
KDM4E B2RXH2 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TDP2 O95551 1/20 0.37
NSD2 O96028 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8404448 0.88 GPR3 (0.59) GPR3HTTALDH1A1HSD17B10CYP1A2
Ammonia Solution, Strong SCHEMBL27764235 0.86 GPR3 (0.56) GPR3HTTALDH1A1HSD17B10CYP1A2
SCHEMBL11732580 0.72 GPR3 (0.54) GPR3HTTALDH1A1HSD17B10CYP1A2
Formamide SCHEMBL28940988 0.71 MAPT (0.48) GPR3ERN1HTTALDH1A1HSD17B10
SCHEMBL8572508 0.70 LCK (0.54) GPR3HTTALDH1A1HSD17B10CYP1A2
SCHEMBL30471260 0.69 LCK (0.67) GPR3HTTALDH1A1HSD17B10CYP1A2
Formamide SCHEMBL28690144 0.69 HSD17B10 (0.55) GPR3ERN1HTTALDH1A1HSD17B10
SCHEMBL22124889 0.68 GPR3 (0.54) GPR3ALDH1A1HSD17B10CYP1A2HPGD
SCHEMBL22124938 0.68 GPR3 (0.54) GPR3ERN1HTTALDH1A1HSD17B10
SCHEMBL19864878 0.68 GPR3 (0.54) GPR3HTTALDH1A1HSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113195455-A Herbicidal cinnolinium compounds 先正达农作物保护股份公司 2021-07-30 CN disclosed