SCHEMBL28629555

SCHEMBL28629555

CC(C)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)cc(C(=O)O)c1Cl.O=c1cc[nH]c(=O)n1F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6899016 0.88 NOTUM (0.35) NOTUM
SCHEMBL8872127 0.79 NOTUM (0.33) NOTUM
SCHEMBL9396141 0.73 NOTUM (0.30) NOTUM
SCHEMBL1807362 0.72 TDP1 (0.52) NOTUM
SCHEMBL8871917 0.71 NOTUM (0.35) NOTUM
SCHEMBL8871942 0.69 NOTUM (0.36) NOTUM
SCHEMBL8872129 0.69 NOTUM (0.32) NOTUM
SCHEMBL2964906 0.67 TDP1 (0.36) NOTUM
SCHEMBL2961429 0.67 TDP1 (0.36) NOTUM
SCHEMBL20356681 0.66 NOTUM (0.36) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110997838-B Silicone-polyether copolymers, sealants including silicone-polyether copolymers, and related methods 美国陶氏有机硅公司 2021-10-01 CN disclosed
CN-110997839-B Silicone-polyether copolymer, method of preparing silicone-polyether copolymer, and sealant including silicone-polyether copolymer 美国陶氏有机硅公司 2021-09-14 CN disclosed
CN-110997840-B Silicone-polyether copolymers, isocyanate-functionalized silicone-polyether copolymers formed therewith, silicone-polyether-urethane copolymers, sealants including the same, and related methods 美国陶氏有机硅公司 2021-09-07 CN disclosed