Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2961429 | 1.00 | TDP1 (0.36) | TDP1CTSBLMNATHRBPPARG | |
| SCHEMBL6552716 | 0.92 | LMNA (0.36) | TDP1CTSBLMNATHRBPPARG | |
| SCHEMBL2966447 | 0.92 | LMNA (0.36) | TDP1CTSBLMNATHRBPPARG | |
| SCHEMBL2968009 | 0.92 | LMNA (0.36) | TDP1CTSBLMNATHRBPPARG | |
| SCHEMBL6553961 | 0.91 | LMNA (0.36) | TDP1CTSBLMNATHRBPPARG | |
| SCHEMBL44446 | 0.91 | ALDH1A1 (0.38) | TDP1CTSBLMNATHRBNOTUM | |
| SCHEMBL4897613 | 0.91 | ALDH1A1 (0.38) | TDP1CTSBLMNATHRBNOTUM | |
| SCHEMBL7949966 | 0.90 | LMNA (0.39) | TDP1CTSBLMNATHRBPPARG | |
| SCHEMBL5691797 | 0.90 | LMNA (0.39) | TDP1CTSBLMNATHRBPPARG | |
| SCHEMBL6553650 | 0.89 | CYP4F2 (0.34) | TDP1CTSBLMNATHRBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436680-B1 | HETEROCYCLIC COMPOUNDS | CIBA GEIGY AG (CH) | 1994-09-07 | — | — | EP | claimed |
| US-7767624-B2 | 3-Heterocyclyl substituted benzoic acid derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2010-08-03 | — | — | US | disclosed |
| US-20050239655-A1 | 3-heterocyclyl substituted benzoic acid derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239655-A1 | 3-heterocyclyl substituted benzoic acid derivatives | DDT, CBR3, BROX | TDP1 1161/4885CTSB 4324/4885LMNA 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.