Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 5/20 | 0.33 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820640 | 1.00 | USP2 (0.40) | USP2SMN1; SMN2ADRA2AADRA1APPARG | |
| SCHEMBL19361582 | 0.92 | USP2 (0.39) | USP2SMN1; SMN2ADRA2AADRA1APPARG | |
| SCHEMBL19361585 | 0.90 | CYP1A2 (0.34) | USP2SMN1; SMN2KDM4ECYP1A2CYP2C19 | |
| SCHEMBL18821185 | 0.90 | KCNH2 (0.38) | USP2SMN1; SMN2ADRA2AADRA1APPARG | |
| SCHEMBL18907014 | 0.87 | USP2 (0.41) | USP2SMN1; SMN2KDM4ECYP1A2CYP3A4 | |
| SCHEMBL18821415 | 0.85 | FAAH (0.36) | SMN1; SMN2PPARGCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL18821010 | 0.85 | FAAH (0.36) | SMN1; SMN2PPARGCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL19361586 | 0.85 | KDM4E (0.38) | ADRA2AADRA1APPARGPPARDPPARA | |
| SCHEMBL18907896 | 0.85 | MMEL1 (0.34) | USP2SMN1; SMN2ADRA2AADRA1APPARG | |
| SCHEMBL18909761 | 0.84 | USP2 (0.39) | USP2SMN1; SMN2KDM4EHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349995-B | Pyrazole ACC inhibitors and uses thereof | 吉利德阿波罗公司 | 2021-08-03 | — | — | CN | disclosed |