Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.69 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.63 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.63 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19433118 | 0.96 | ESR1 (0.72) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL1547661 | 0.95 | ESR1 (0.71) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL14790189 | 0.93 | ESR1 (0.64) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7991514 | 0.93 | ESR1 (0.73) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7998229 | 0.93 | ESR1 (0.73) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7994855 | 0.93 | ESR1 (0.73) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7994946 | 0.93 | ESR1 (0.73) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7994799 | 0.93 | ESR1 (0.73) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7991491 | 0.93 | ESR1 (0.73) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7980640 | 0.93 | ESR1 (0.73) | ESR1TSHRLMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133466-B1 | A PROCESS FOR THE PREPARATION OF N,N'-BIS 2, 3-DIHYDROXYPROPYL] -5-[(HYDROXYACETYL) METHYLAMINO]-2, 4,6-TRIIODO-1, 3-BENZENEDI CARBOXAMIDE | BRACCO INT BV (NL) | 2003-08-20 | — | — | EP | claimed |
| US-6420603-B1 | ESTERIFICATION OF 5-HYDROXYISOPHTHALIC ACID, AMIDATION WITH ISOSERINOL, IODINATION AND ALKYLATION | BRACCO INTERNATIONAL B.V. (NL) | 2002-07-16 | — | — | US | claimed |
| CN-112479888-B | Compound, polymer, patterning material, patterning method, and method for manufacturing semiconductor device | 铠侠股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-112479888-A | Compound, polymer, pattern forming material, pattern forming method, and method for manufacturing semiconductor device | 铠侠股份有限公司 | 2021-03-12 | — | — | CN | disclosed |
| US-20170183277-A1 | MOLECULAR SIEVES MEDIATED UNSATURATED HYDROCARBON SEPARATION AND RELATED COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2017-06-29 | — | — | US | disclosed |
| US-20170081466-A1 | ASSOCIATIVE POLYMERS FOR USE IN A FLOW AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | NASA | 2017-03-23 | — | — | US | disclosed |
| EP-2254850-B1 | PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS | BRACCO IMAGING SPA (IT) | 2016-06-22 | — | — | EP | disclosed |
| US-9193659-B2 | Process for the iodination of aromatic compounds | BRACCO IMAGING S.P.A. (IT) | 2015-11-24 | — | — | US | disclosed |
| EP-2580187-B1 | Process for the iodination of phenolic derivatives | BRACCO IMAGING SPA (IT) | 2015-05-27 | — | — | EP | disclosed |
| US-8766003-B2 | Process for the iodination of phenolic derivatives | BRACCO IMAGING S.P.A. (IT) | 2014-07-01 | — | — | US | disclosed |
| US-8766003-B2 | Process for the iodination of phenolic derivatives | BRACCO IMAGING S.P.A. (IT) | 2014-07-01 | — | — | US | disclosed |
| EP-2254850-A2 | PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS | Bracco Imaging S.p.A (IT) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009103666-A2 | PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS | BRACCO IMAGING SPA (IT) | 2009-08-27 | — | — | WO | disclosed |
| EP-2093206-A1 | Process for the iodination of aromatic compounds | BRACCO IMAGING S.p.A. (IT) | 2009-08-26 | — | — | EP | disclosed |
| WO-2004071376-A2 | ORAL CARE COMPOSITION COMPRISING AN ANTIMICROBIAL AGENT | UNILEVER N.V. (NL) | 2004-08-26 | — | — | WO | disclosed |
| US-20040141929-A1 | Composition | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-07-22 | — | — | US | disclosed |
| US-20040141928-A1 | Composition | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-07-22 | — | — | US | disclosed |
| WO-2004047782-A1 | ORAL COMPOSITIONS COMPRISING SALTS OF ALKYL HYDROXYBENZOATES | UNILEVER N.V. (NL) | 2004-06-10 | — | — | WO | disclosed |
| EP-1133466-B1 | A PROCESS FOR THE PREPARATION OF N,N'-BIS 2, 3-DIHYDROXYPROPYL] -5-[(HYDROXYACETYL) METHYLAMINO]-2, 4,6-TRIIODO-1, 3-BENZENEDI CARBOXAMIDE | BRACCO INT BV (NL) | 2003-08-20 | — | — | EP | disclosed |
| US-6420603-B1 | ESTERIFICATION OF 5-HYDROXYISOPHTHALIC ACID, AMIDATION WITH ISOSERINOL, IODINATION AND ALKYLATION | BRACCO INTERNATIONAL B.V. (NL) | 2002-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040141929-A1 | Composition | NHERF1, C1R, CFH | ESR1 2717/4885TSHR 1106/4885LMNA 2128/4885 |
| US-20040141928-A1 | Composition | CPT1A, EBP, UQCRC1 | ESR1 3177/4885TSHR 3238/4885LMNA 695/4885 |
| US-20170183277-A1 | MOLECULAR SIEVES MEDIATED UNSATURATED HYDROCARBON SEPARATION AND RELATED COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS | ORAI2, ORAI3, KCNJ2 | ESR1 208/4885TSHR 4062/4885LMNA 664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.