Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259291 | 0.80 | PGR (0.44) | HTTPSDPGRTLR2TLR1 | |
| SCHEMBL3757135 | 0.77 | HTT (0.51) | HTTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL18581123 | 0.76 | MEN1 (0.43) | HTTPGRTLR2TLR1ALDH1A1 | |
| SCHEMBL18579333 | 0.76 | PTGS2 (0.43) | HTTPSDPGRTLR2TLR1 | |
| SCHEMBL18579331 | 0.76 | PTGS2 (0.43) | HTTPSDPGRTLR2TLR1 | |
| SCHEMBL18579338 | 0.76 | KCNH2 (0.40) | HTTPSDPGRALDH1A1KMT2A | |
| SCHEMBL18581057 | 0.76 | TRPV1 (0.42) | HTTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL18580989 | 0.74 | SMN1; SMN2 (0.41) | HTTPSDPGRTLR2TLR1 | |
| SCHEMBL18579379 | 0.74 | PGR (0.38) | HTTPSDPGRTLR2TLR1 | |
| SCHEMBL18618047 | 0.74 | PGR (0.38) | HTTPSDPGRTLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108025189-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2021-07-02 | — | — | CN | disclosed |