Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425666 | 0.80 | MEN1 (0.70) | KMT2AMEN1EPHX2 | |
| SCHEMBL22291866 | 0.78 | POLB (0.81) | HPGD | |
| SCHEMBL11367962 | 0.78 | HPGD (0.82) | KMT2AMEN1HPGD | |
| SCHEMBL9426051 | 0.78 | CYP1A2 (0.66) | HPGD | |
| SCHEMBL11415704 | 0.77 | KMT2A (0.65) | KMT2AMEN1 | |
| SCHEMBL10773005 | 0.76 | PTGS2 (0.59) | HTR2CHTR2A | |
| SCHEMBL10772012 | 0.76 | PTGS2 (0.59) | HTR2CHTR2A | |
| SCHEMBL10774727 | 0.76 | PTGS2 (0.59) | HTR2CHTR2A | |
| SCHEMBL8559148 | 0.76 | MEN1 (0.62) | KMT2AMEN1 | |
| SCHEMBL27516231 | 0.76 | KMT2A (0.85) | KMT2AMEN1HTR1AHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516926-B | Preparation and application of piperlonguminine derivative | 四川大学 | 2021-09-17 | — | — | CN | disclosed |