Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.58 |
| ▸ | TUBB | P07437 | 2/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10773005 | 1.00 | PTGS2 (0.59) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10774727 | 1.00 | PTGS2 (0.59) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5514786 | 0.98 | PTGS2 (0.61) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5568951 | 0.92 | PTGS2 (0.63) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7424861 | 0.90 | HTR2A (0.69) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1171730 | 0.84 | PPARG (0.47) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2500546 | 0.84 | PTGS2 (0.68) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23534141 | 0.83 | TUBB4A (0.57) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19348319 | 0.83 | PPARG (0.53) | PTGS2HTR2AALOX5PPARGPPARA | |
| SCHEMBL4740186 | 0.83 | TUBB4A (0.61) | PTGS2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229944-A2 | Novel tetrahydroisoquinoline derivatives | SYNTEX (U.S.A.) INC. (US) | 1987-07-29 | — | — | EP | disclosed |