Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.51 |
| ▸ | HTR2C | P28335 | 7/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040042 | 0.86 | MAP4K4 (0.55) | DRD4HTR2CDRD2DRD3MAPT | |
| SCHEMBL3814933 | 0.85 | RAB9A (0.63) | DRD4DRD2DRD3MAPTKDM4E | |
| SCHEMBL1194641 | 0.84 | DRD2 (0.51) | DRD4DRD2DRD3MAPTKDM4E | |
| SCHEMBL31517482 | 0.84 | MAPT (0.50) | DRD4DRD2MAPTKDM4ERAB9A | |
| SCHEMBL19510721 | 0.84 | MAPT (0.49) | DRD4DRD2DRD3MAPTKDM4E | |
| SCHEMBL11493879 | 0.84 | QPCT (0.49) | DRD4DRD2MAPTKDM4ERAB9A | |
| SCHEMBL31517290 | 0.84 | MAPT (0.49) | DRD4HTR2CDRD2DRD3MAPT | |
| SCHEMBL10384035 | 0.83 | PTGDR2 (0.50) | DRD4HTR2CDRD2DRD3MAPT | |
| SCHEMBL31517715 | 0.83 | MAPT (0.50) | DRD4DRD2DRD3MAPTKDM4E | |
| SCHEMBL31517634 | 0.82 | DRD4 (0.53) | DRD4HTR2CDRD2DRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025040546-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-02-27 | — | — | WO | disclosed |
| CN-109867666-B | Aromatic acetamide compound containing isothiazole ring and application thereof | 沈阳中化农药化工研发有限公司 | 2021-09-07 | — | — | CN | disclosed |