Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25433106 | 0.74 | SCD (0.47) | ALDH1A1CACNA1GCACNA1HCACNA1IMAPT | |
| SCHEMBL6746046 | 0.72 | KDM4E (0.60) | KDM4EALDH1A1POLBOPRD1ADRA1D | |
| SCHEMBL1243976 | 0.72 | CNR2 (0.55) | BRD4BRD2BRD3BRDTTP53 | |
| SCHEMBL26637780 | 0.71 | GAA (0.49) | KDM4EALDH1A1POLBOPRD1ADRA1D | |
| SCHEMBL10965858 | 0.71 | BRD4 (0.50) | BRD4BRD2BRD3BRDTTP53 | |
| SCHEMBL17042553 | 0.70 | CYP2D6 (0.55) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL10567213 | 0.70 | OPRM1 (0.53) | KDM4EALDH1A1POLBOPRD1ADRA1D | |
| SCHEMBL25433618 | 0.70 | HDAC9 (0.43) | TP53ALDH1A1LMNACACNA1GCACNA1H | |
| SCHEMBL349195 | 0.70 | MEN1 (0.56) | OPRD1MEN1KMT2A | |
| SCHEMBL8503086 | 0.70 | CA12 (0.57) | BRD4BRD2BRD3BRDTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693701-B | Modulators of ATP-binding cassette transporters | 弗特克斯药品有限公司 | 2021-08-10 | — | — | CN | disclosed |