Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.59 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567213 | 0.92 | OPRM1 (0.53) | KDM4ENPSR1OPRM1OPRD1OPRK1 | |
| SCHEMBL4881599 | 0.88 | L3MBTL1 (0.60) | KDM4ENPSR1CYP2D6ALDH1A1KCNH2 | |
| SCHEMBL6200425 | 0.88 | KDM4E (0.53) | KDM4ENPSR1OPRM1OPRL1ALDH1A1 | |
| SCHEMBL11282136 | 0.86 | OPRM1 (0.80) | KDM4ENPSR1OPRM1OPRD1OPRK1 | |
| SCHEMBL26637780 | 0.86 | GAA (0.49) | KDM4ENPSR1OPRM1OPRD1OPRK1 | |
| SCHEMBL5764552 | 0.85 | KDM4E (0.51) | KDM4EOPRM1OPRL1ALDH1A1 | |
| SCHEMBL5764547 | 0.85 | KDM4E (0.51) | KDM4EOPRM1OPRL1ALDH1A1 | |
| SCHEMBL2789658 | 0.85 | KDM4E (0.61) | KDM4ENPSR1OPRM1OPRD1OPRK1 | |
| SCHEMBL191606 | 0.85 | DRD2 (0.59) | KCNA3ADRA1AADRA1DDRD2DRD4 | |
| SCHEMBL23535114 | 0.84 | DRD2 (0.51) | KDM4ENPSR1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| WO-1998007722-A1 | QUATERNARY AMMONIUM COMPOUNDS AS TACHYKININ ANTAGONIST | PFIZER LIMITED (GB) | 1998-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | KDM4E 1573/4885NPSR1 556/4885OPRM1 1879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.