Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.52 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.45 |
| ▸ | SLC2A9 | Q9NRM0 | 2/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30179859 | 1.00 | CYP19A1 (0.52) | CYP19A1ROR1SLC22A12SLC2A9XDH | |
| SCHEMBL5421488 | 0.85 | ROR1 (0.57) | CYP19A1ROR1ACHEMEN1POLB | |
| SCHEMBL28635979 | 0.72 | SLC22A12 (0.76) | CYP19A1SLC22A12SLC2A9XDHKDM4E | |
| SCHEMBL25437506 | 0.72 | MAOB (0.74) | CYP19A1ROR1KDM4EMAPTCYP3A4 | |
| SCHEMBL5421506 | 0.71 | CYP19A1 (0.38) | CYP19A1ROR1POLB | |
| SCHEMBL28635972 | 0.70 | SLC22A12 (0.52) | CYP19A1SLC22A12SLC2A9XDHACHE | |
| SCHEMBL13140976 | 0.69 | SLC22A12 (0.64) | CYP19A1SLC22A12SLC2A9XDHKDM4E | |
| SCHEMBL5518672 | 0.69 | SLC22A12 (0.77) | CYP19A1SLC22A12SLC2A9XDHKDM4E | |
| SCHEMBL22465343 | 0.69 | PDCD1 (0.51) | CYP19A1ROR1ACHEMAPTKMT2A | |
| SCHEMBL22465743 | 0.69 | PDCD1 (0.55) | CYP19A1ROR1XDHACHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661738-B | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112661738-A | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2021-04-16 | — | — | CN | disclosed |