Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.77 |
| ▸ | SLC2A9 | Q9NRM0 | 2/20 | 0.77 |
| ▸ | XDH | P47989 | 1/20 | 0.77 |
| ▸ | ESR1 | P03372 | 3/20 | 0.69 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.69 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.69 |
| ▸ | PRKCA | P17252 | 1/20 | 0.69 |
| ▸ | BACE1 | P56817 | 1/20 | 0.69 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.63 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13140976 | 0.92 | SLC22A12 (0.64) | SLC22A12SLC2A9XDHESR1AKR1B10 | |
| SCHEMBL5513740 | 0.92 | ABCG2 (0.66) | SLC22A12SLC2A9XDHESR1AKR1B10 | |
| SCHEMBL5513744 | 0.92 | ABCG2 (0.66) | SLC22A12SLC2A9XDHESR1AKR1B10 | |
| Isobavachin SCHEMBL31620056 | 0.87 | SLC22A12 (1.00) | SLC22A12SLC2A9XDHESR1AKR1B10 | |
| Isobavachin SCHEMBL1170628 | 0.87 | SLC22A12 (1.00) | SLC22A12SLC2A9XDHESR1AKR1B10 | |
| Isobavachin SCHEMBL27013463 | 0.87 | SLC22A12 (1.00) | SLC22A12SLC2A9XDHESR1AKR1B10 | |
| 7-O-Methylisoxanthohumol SCHEMBL29929829 | 0.84 | ESR1 (0.87) | SLC22A12SLC2A9XDHESR1AKR1B10 | |
| Munduleaflavanone B SCHEMBL14049994 | 0.84 | ESR1 (0.87) | SLC22A12SLC2A9XDHESR1AKR1B10 | |
| Isoxanthohumol SCHEMBL904557 | 0.82 | ESR1 (1.00) | SLC22A12SLC2A9XDHESR1AKR1B10 | |
| Isoxanthohumol SCHEMBL29743582 | 0.82 | ESR1 (1.00) | SLC22A12SLC2A9XDHESR1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | claimed |
| EP-1623704-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-08 | — | — | EP | claimed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| EP-1623704-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | FABP4, GPR119, IAPP | SLC22A12 241/4885SLC2A9 44/4885XDH 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.