Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.52 |
| ▸ | SLC2A9 | Q9NRM0 | 2/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635979 | 0.77 | SLC22A12 (0.76) | SLC22A12SLC2A9XDHPOLBMAPT | |
| SCHEMBL28635976 | 0.74 | KDM4E (0.32) | MAPTKDM4E | |
| SCHEMBL28629171 | 0.70 | MAOB (0.62) | CYP19A1ESR2MAOACYP3A4 | |
| SCHEMBL28630190 | 0.70 | CYP19A1 (0.52) | SLC22A12SLC2A9XDHPOLBMAPT | |
| SCHEMBL30179859 | 0.70 | CYP19A1 (0.52) | SLC22A12SLC2A9XDHPOLBMAPT | |
| Isobavachin SCHEMBL31620056 | 0.68 | SLC22A12 (1.00) | SLC22A12SLC2A9XDHPOLBMAPT | |
| Isobavachin SCHEMBL27013463 | 0.68 | SLC22A12 (1.00) | SLC22A12SLC2A9XDHPOLBMAPT | |
| SCHEMBL28625916 | 0.68 | CYP19A1 (0.78) | MAPTPTPN1CYP19A1ESR2MAOA | |
| SCHEMBL13178896 | 0.66 | SLC22A12 (0.66) | SLC22A12SLC2A9XDHPOLBMAPT | |
| SCHEMBL17387105 | 0.65 | MAPT (0.65) | SLC22A12SLC2A9XDHPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661738-B | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112661738-A | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2021-04-16 | — | — | CN | disclosed |