Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22218494 | 0.89 | LTB4R2 (0.46) | LTB4R2MAPTMEN1NPC1RAB9A | |
| SCHEMBL16211634 | 0.89 | LTB4R2 (0.44) | LTB4R2MAPTMEN1NPC1RAB9A | |
| SCHEMBL20236537 | 0.88 | LTB4R2 (0.46) | LTB4R2MAPTMEN1NPC1RAB9A | |
| SCHEMBL16211288 | 0.88 | HDAC1 (0.50) | LTB4R2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL20236124 | 0.88 | NR1H4 (0.44) | LTB4R2MAPTMEN1NPC1RAB9A | |
| SCHEMBL28627937 | 0.88 | LMNA (0.43) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28634661 | 0.88 | BCL2A1 (0.46) | MAPTNPC1RAB9AKMT2ANR1H4 | |
| SCHEMBL28632328 | 0.88 | RAB9A (0.40) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28645488 | 0.88 | MAPK1 (0.43) | LTB4R2MAPTMEN1NPC1RAB9A | |
| SCHEMBL28630226 | 0.87 | MEN1 (0.38) | MAPTMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137518-B | 1,3, 4-oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same | 株式会社钟根堂 | 2021-08-31 | — | — | CN | disclosed |