Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220153 | 0.97 | BTK (0.54) | BTKCA1CA2GAAEPHX1 | |
| SCHEMBL117269 | 0.91 | BTK (0.51) | BTKCA1CA2GAAEPHX1 | |
| Bicarbonate SCHEMBL3395208 | 0.88 | BTK (0.53) | BTKCA1CA2GAAEPHX1 | |
| SCHEMBL10239204 | 0.86 | BTK (0.55) | BTKCA1CA2GAAEPHX1 | |
| SCHEMBL21597571 | 0.86 | BTK (0.55) | BTKCA1CA2GAAEPHX1 | |
| SCHEMBL132145 | 0.86 | BTK (0.55) | BTKCA1CA2GAAEPHX1 | |
| SCHEMBL24874466 | 0.85 | BTK (0.54) | BTKCA1CA2GAAEPHX1 | |
| SCHEMBL13735251 | 0.85 | BTK (0.54) | BTKCA1CA2GAAEPHX1 | |
| SCHEMBL8320677 | 0.83 | CTSK (0.50) | BTKCA1CA2GAAEPHX1 | |
| SCHEMBL720530 | 0.83 | CTSK (0.50) | BTKCA1CA2GAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423433-A | Nanoparticles carrying antifolates and their use in medicine | MIDA科技有限公司 | 2021-09-21 | — | — | CN | disclosed |