Sugi Predict

Sugi Predict / Compounds / SCHEMBL117269

SCHEMBL117269

SCHEMBL117269

CC(C)(C)OC(=O)NC1CCC(=O)CC1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ BTK Q06187 1/20 0.51
▸ GAA P10253 2/20 0.50
▸ NFKB1 P19838 1/20 0.49
▸ NFKB2 Q00653 1/20 0.49
▸ RELA Q04206 1/20 0.49
▸ KDM1A O60341 1/20 0.48
▸ MAOB P27338 1/20 0.48
▸ CTSK P43235 2/20 0.48
▸ EPHX1 P07099 1/20 0.45
▸ DRD2 P14416 2/20 0.45
▸ EPHX2 P34913 1/20 0.44
▸ CA1 P00915 1/20 0.43
▸ CA2 P00918 1/20 0.43
▸ JAK1 P23458 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ KCNA3 P22001 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL3395208 0.97 BTK (0.53) BTKGAANFKB1NFKB2RELA
SCHEMBL8220153 0.94 BTK (0.54) BTKGAANFKB1NFKB2RELA
SCHEMBL720530 0.91 CTSK (0.50) BTKGAANFKB1NFKB2RELA
SCHEMBL8320677 0.91 CTSK (0.50) BTKGAANFKB1NFKB2RELA
SCHEMBL720531 0.91 CTSK (0.50) BTKGAANFKB1NFKB2RELA
Ammonia Solution, Strong SCHEMBL28630271 0.91 BTK (0.51) BTKGAANFKB1NFKB2RELA
SCHEMBL26135662 0.86 BTK (0.51) BTKGAANFKB1NFKB2RELA
SCHEMBL10343938 0.85 BTK (0.61) BTKGAANFKB1NFKB2RELA
SCHEMBL3702152 0.85 BTK (0.61) BTKGAANFKB1NFKB2RELA
SCHEMBL3702157 0.85 BTK (0.61) BTKGAANFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117180192-A PH response star-shaped polymer micelle and preparation method and application thereof 广东工业大学 2023-12-08 — — CN claimed
CN-117180193-A pH and reduction dual-response polymer crosslinked micelle and preparation method thereof 广东工业大学 2023-12-08 — — CN claimed
CN-115040478-B pH/reduction dual-response polymer crosslinked micelle and preparation method thereof 广东工业大学 2023-10-13 — — CN claimed
CN-115010913-B PH/reduction dual-response polymer micelle and preparation method and application thereof 广东工业大学 2023-05-26 — — CN claimed
CN-114524799-B HDAC inhibitor and preparation method and application thereof 沈阳药科大学 2023-05-26 — — CN claimed
CN-115850156-A Method for purifying difluoride compound 上海泰坦科技股份有限公司 2023-03-28 — — CN claimed
CN-115040478-A PH/reduction dual-response polymer crosslinked micelle and preparation method thereof 广东工业大学 2022-09-13 — — CN claimed
CN-115010913-A PH/reduction dual-response polymer micelle and preparation method and application thereof 广东工业大学 2022-09-06 — — CN claimed
CN-114524799-A HDAC inhibitor and preparation method and application thereof 沈阳药科大学 2022-05-24 — — CN claimed
CN-109535019-A 1,1a, 6,6a- tetrahydro cyclopropyl simultaneously [a] indenes -1- amine derivative and the preparation method and application thereof 华东师范大学 2019-03-29 — — CN claimed
CN-108530302-A 2`, 3`- dihydro spiral shell [cyclopropane -1,1`- indenes] -2- amine derivatives and its preparation method and application 华东师范大学 2018-09-14 — — CN claimed
US-20260146043-A1 CRYSTALLINE FORMS OF PYRIMIDINO DIAZEPINE DERIVATIVE CYCLACEL PHARMACEUTICALS INC. (US) 2026-05-28 — — US disclosed
US-12624004-B2 Opioid receptor agonist, preparation method therefor and pharmaceutical use thereof FUDAN UNIVERSITY (CN) 2026-05-12 — — US disclosed
US-20260116884-A1 PROTAC CHIMERIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO LTD (CN) 2026-04-30 — — US disclosed
EP-3985001-B1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING A CANCER SERVIER LAB (FR) 2026-04-29 — — EP disclosed
EP-0978516-A1 1-CYCLOALKYL-1,8-NAPHTHYRIDIN-4-ONE DERIVATIVES WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY SUNTORY LIMITED (JP) 2000-02-09 — — EP disclosed
EP-0899261-A1 Optical active 1,4-dihydropyridine compounds as bradykinin antagonists PFIZER INC. (US) 1999-03-03 — — EP disclosed
US-5691323-A BENZIMIDAZOL-2-ONES MERCK & CO., INC. (US) 1997-11-25 — — US disclosed
US-5574044-A BENZIMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF MYOPIA MERCK & CO., INC. (US) 1996-11-12 — — US disclosed
WO-1996013262-A1 MUSCARINE ANTAGONISTS MERCK & CO., INC. (US) 1996-05-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624004-B2 Opioid receptor agonist, preparation method therefor and pharmaceutical use thereof OPRM1, OPRD1, OPRK1 BTK 1542/4885GAA 4224/4885NFKB1 2443/4885
US-20260146043-A1 CRYSTALLINE FORMS OF PYRIMIDINO DIAZEPINE DERIVATIVE CTNND1, CCNC, SFN BTK 2156/4885GAA 3869/4885NFKB1 488/4885
US-20260116884-A1 PROTAC CHIMERIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF CXCR1, TXK, CXCR4 BTK 977/4885GAA 4574/4885NFKB1 508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.