Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626848 | 0.91 | ALDH1A1 (0.56) | LMNANPSR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL18257057 | 0.91 | ALDH1A1 (0.56) | LMNANPSR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28625164 | 0.90 | ALDH1A1 (0.66) | LMNANPSR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28622865 | 0.90 | ALDH1A1 (0.55) | LMNANPSR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28923360 | 0.90 | ALDH1A1 (0.55) | LMNANPSR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11096695 | 0.90 | MEN1 (0.61) | LMNANPSR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28628871 | 0.90 | MEN1 (0.61) | LMNANPSR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28627337 | 0.89 | MEN1 (0.63) | LMNANPSR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3575310 | 0.89 | MEN1 (0.63) | LMNANPSR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28631554 | 0.89 | ALDH1A1 (0.53) | LMNANPSR1ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641878-B | DIPROVOCIM: effective TLR agonist | 斯克里普斯研究学院 | 2021-09-14 | — | — | CN | disclosed |