Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096695 | 1.00 | MEN1 (0.61) | MEN1KMT2AATMCYP3A4MAPT | |
| SCHEMBL28622807 | 0.94 | CYP3A4 (0.57) | MEN1KMT2AATMCYP3A4MAPT | |
| SCHEMBL10709019 | 0.94 | FKBP1A (0.68) | MEN1KMT2AATMFKBP1ASMN1; SMN2 | |
| SCHEMBL23565690 | 0.90 | FKBP1A (0.64) | FKBP1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18257057 | 0.90 | ALDH1A1 (0.56) | MEN1KMT2AATMCYP3A4MAPT | |
| SCHEMBL28630307 | 0.90 | LMNA (0.60) | MEN1KMT2AATMCYP3A4MAPT | |
| SCHEMBL28626848 | 0.90 | ALDH1A1 (0.56) | MEN1KMT2AATMCYP3A4MAPT | |
| SCHEMBL28923360 | 0.89 | ALDH1A1 (0.55) | MEN1KMT2AATMCYP3A4MAPT | |
| SCHEMBL28625164 | 0.89 | ALDH1A1 (0.66) | MEN1KMT2AATMCYP3A4MAPT | |
| SCHEMBL28622865 | 0.89 | ALDH1A1 (0.55) | MEN1KMT2AATMCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641878-B | DIPROVOCIM: effective TLR agonist | 斯克里普斯研究学院 | 2021-09-14 | — | — | CN | disclosed |