SCHEMBL2863035

SCHEMBL2863035

NC(=O)CC[C@H]1CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8134196 1.00
SCHEMBL2863037 1.00
SCHEMBL1499252 0.88
SCHEMBL5370030 0.84 ALDH1A1 (0.50)
SCHEMBL3630010 0.78 ALDH1A1 (0.36)
SCHEMBL8472632 0.77
SCHEMBL1122114 0.77
SCHEMBL6308650 0.77
SCHEMBL14725898 0.76 PRKD3 (0.33)
SCHEMBL2656786 0.76 LMNA (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040006238-A1 Process to produce oxazolidinones PHARMACIA & UPJOHN COMPANY 2004-01-08 US claimed
US-20030216572-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY 2003-11-20 US claimed
US-20030130509-A1 PROCESS TO PRODUCE 3-CARBON AMINO ALCOHOL SALTS PHARMACIA & UPJOHN COMPANY 2003-07-10 US claimed
US-20030065219-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY 2003-04-03 US claimed
US-20020095054-A1 Process to produce oxazolidinones PHARMACIA & UPJOHN COMPANY 2002-07-18 US claimed
US-20020032348-A1 Process to produce oxazolidinones PEARLMAN BRUCE ALLEN (US) 2002-03-14 US claimed
WO-2010084514-A2 A PROCESS FOR THE PREPARATION OF (5S)-(N)-[[3-[3-FLUORO-4-(4-MORPHOLINYL) PHENYL]-2-OXO-5-OXAZOLIDINYL] METHYL] ACETAMIDE NEULAND LABORATORIES LTD. (IN) 2010-07-29 WO disclosed
US-20090221655-A1 ANTIBACTERIAL AGENTS PITZER, INC. (US) 2009-09-03 US disclosed
EP-1028940-B1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN CO LLC (US) 2007-04-18 EP disclosed
EP-1772453-A1 Process to produce Oxazolidinones Pharmacia & Upjohn Company LLC (US) 2007-04-11 EP disclosed
EP-1328509-B1 METHODS OF PRODUCING OXAZOLIDINONE COMPOUNDS PHARMACIA & UPJOHN CO LLC (US) 2006-03-22 EP disclosed
US-6998420-B2 Oxazolidinone compounds PHARMACIA & UPJOHN COMPANY (US) 2006-02-14 US disclosed
US-6833453-B2 As an example, manufacturing a 5-(tert-butylcarbamoyl)-amino-methyl-oxazolidinone by condensing a carbamate with a tert-butylcarbamoyl protected derivative of glycidylamine or a 3-amino-1-halopropanol PHARMACIA & UPJOHN COMPANY 2004-12-21 US disclosed
US-6362334-B1 OXAZOLIDINONE PHTHALAMIDE PHARMACIA & UPJOHN COMPANY 2002-03-26 US disclosed
US-20020032348-A1 Process to produce oxazolidinones PEARLMAN BRUCE ALLEN (US) 2002-03-14 US disclosed
EP-1049701-A1 TRICYCLIC INDOLENE SUBSTITUTED OXAZOLIDINONES BAYER AG (DE) 2000-11-08 EP disclosed
EP-1028940-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA &amp; UPJOHN COMPANY (US) 2000-08-23 EP disclosed
US-6107519-A Process to produce oxazolidinones PHARMACIA & UPJOHN COMPANY (US) 2000-08-22 US disclosed
WO-1999037652-A1 TRICYCLIC INDOLENE SUBSTITUTED OXAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1999-07-29 WO disclosed
WO-1999024393-A1 PROCESS TO PRODUCE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY (US) 1999-05-20 WO disclosed