Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13698518 | 0.85 | SLC18A3 (0.66) | SLC18A3ADRB1ALDH1A1TSHRKMT2A | |
| SCHEMBL3436477 | 0.83 | AKR1C3 (0.55) | SLC18A3ADRB1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3710253 | 0.83 | ADRB1 (0.65) | SLC18A3ADRB1TSHRKMT2A | |
| SCHEMBL173027 | 0.82 | ADRB1 (0.62) | SLC18A3ADRB1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30656303 | 0.82 | ADRB1 (0.62) | SLC18A3ADRB1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL24124031 | 0.81 | GAA (0.50) | SLC18A3ALDH1A1SMN1; SMN2LMNAMCOLN3 | |
| Ammonia Solution, Strong SCHEMBL28721086 | 0.81 | ADRB1 (0.60) | SLC18A3ADRB1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3711300 | 0.81 | MAPT (0.70) | ALDH1A1KMT2A | |
| SCHEMBL3709570 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL3706215 | 0.80 | MAPT (0.68) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428508-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | Astellas Pharma Inc. (JP) | 2012-03-14 | — | — | EP | disclosed |