Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.65 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | KHK | P50053 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13698518 | 0.84 | SLC18A3 (0.66) | ADRB1SLC18A3TSHRKMT2A | |
| SCHEMBL286304 | 0.83 | SLC18A3 (0.56) | ADRB1SLC18A3TSHRKMT2A | |
| SCHEMBL3436477 | 0.81 | AKR1C3 (0.55) | ADRB1SLC18A3TSHRKMT2A | |
| SCHEMBL13698523 | 0.81 | SLC18A3 (0.55) | ADRB1SLC18A3TSHRKMT2A | |
| SCHEMBL3556792 | 0.81 | DRD2 (0.68) | ADRB1HTR1AHTR3A | |
| SCHEMBL4896 | 0.79 | ADRB1 (1.00) | ADRB1HTR7HTR2AHTR1AHTR3A | |
| SCHEMBL29432760 | 0.79 | ADRB1 (1.00) | ADRB1HTR7HTR2AHTR1AHTR3A | |
| SCHEMBL2209183 | 0.79 | ADRB1 (1.00) | ADRB1HTR7HTR2AHTR1AHTR3A | |
| Bromide SCHEMBL10672999 | 0.78 | ADRB1 (0.96) | ADRB1HTR7HTR2AHTR1AHTR3A | |
| Hydrochloric Acid SCHEMBL30182987 | 0.78 | ADRB1 (0.96) | ADRB1HTR7HTR2CHTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |