Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYBB | P04839 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470165 | 0.81 | ATM (0.35) | CYP1A2MAPK1MEN1KMT2AATM | |
| SCHEMBL31748025 | 0.77 | ALOX5 (0.40) | CYP1A2MAPK1TDP1MEN1ALOX15 | |
| SCHEMBL7790465 | 0.77 | ALOX5 (0.36) | CYP2C9NOX1MEN1KMT2AATM | |
| SCHEMBL16787166 | 0.75 | APP (0.34) | MAPTCYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL18961038 | 0.74 | PRKDC (0.32) | ATMPRKDC | |
| SCHEMBL16787210 | 0.74 | APP (0.31) | APPATM | |
| SCHEMBL9778322 | 0.74 | NOX1 (0.51) | MAPTCYP1A2CYP2C9CYP2C19NOX1 | |
| SCHEMBL10513235 | 0.74 | NOX1 (0.55) | MAPTCYP1A2CYP2C9CYP2C19NOX1 | |
| SCHEMBL16787186 | 0.73 | APP (0.33) | MAPTCYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL23546578 | 0.72 | MEN1 (0.41) | SMN1; SMN2MAPK1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292552-B | Benzo five-membered ring aza derivative containing benzophenone group and preparation method and application thereof | 广东工业大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-113292552-A | Benzo five-membered ring aza derivative containing benzophenone group and preparation method and application thereof | 广东工业大学 | 2021-08-24 | — | — | CN | disclosed |