Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27924285 | 0.88 | ALOX5 (0.38) | ALOX5CYP2C9KDM4EALDH1A1NPSR1 | |
| SCHEMBL6450659 | 0.85 | TRPA1 (0.42) | ALOX5CYP2C9KDM4EALDH1A1ATM | |
| SCHEMBL30445395 | 0.83 | BCHE (0.42) | CYP2C9ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL28019646 | 0.83 | P2RX4 (0.35) | ALOX5CYP2C9KDM4EALDH1A1NPSR1 | |
| SCHEMBL9495694 | 0.83 | ALOX5 (0.51) | ALOX5KDM4EALDH1A1KMT2AATM | |
| SCHEMBL11825239 | 0.83 | ALOX5 (0.38) | ALOX5CYP2C9KDM4EALDH1A1NPSR1 | |
| SCHEMBL706922 | 0.83 | ALOX5 (0.38) | ALOX5CYP2C9KDM4EALDH1A1NPSR1 | |
| SCHEMBL28049446 | 0.81 | LMNA (0.38) | CYP2C9KDM4EALDH1A1NPSR1MEN1 | |
| SCHEMBL9496241 | 0.80 | TSHR (0.53) | CYP2C9KDM4EALDH1A1NPSR1MEN1 | |
| SCHEMBL10514539 | 0.79 | TSHR (0.35) | ALOX5ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010025105-A1 | Certain substituted 1-aryl-3-piperazine-1'-yl propanones | MOLECULAR GERIATARICS CORPORATION | 2001-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025105-A1 | Certain substituted 1-aryl-3-piperazine-1'-yl propanones | PSEN1, PSEN2, PRNP | ALOX5 4770/4885CYP2C9 4873/4885NOX1 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.