Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28641973 | 0.70 | TP53 (0.85) | MAPTKDM4ERAB9ANPSR1ALDH1A1 | |
| SCHEMBL28635758 | 0.70 | ALDH1A1 (1.00) | MAPTKDM4ERAB9ANPSR1ALDH1A1 | |
| SCHEMBL28641830 | 0.67 | SMN1; SMN2 (0.72) | MAPTKDM4ERAB9ANPSR1ALDH1A1 | |
| SCHEMBL28923256 | 0.66 | ALDH1A1 (0.83) | MAPTKDM4ERAB9ANPSR1ALDH1A1 | |
| SCHEMBL28639448 | 0.66 | ALDH1A1 (0.83) | MAPTKDM4ERAB9ANPSR1ALDH1A1 | |
| SCHEMBL28631363 | 0.63 | ALDH1A1 (0.77) | MAPTKDM4ERAB9ANPSR1ALDH1A1 | |
| SCHEMBL28631542 | 0.63 | ALDH1A1 (0.77) | MAPTKDM4ERAB9ANPSR1ALDH1A1 | |
| SCHEMBL7532501 | 0.61 | PKM (0.56) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL28637593 | 0.60 | ALDH1A1 (0.73) | MAPTKDM4ERAB9ANPSR1ALDH1A1 | |
| SCHEMBL15883199 | 0.59 | ALDH1A1 (0.55) | MAPTKDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232357-B | Method for catalytically synthesizing 3-pyrroline-2-ketone in emulsion by titanocene dichloride in cooperation with Bronsted acid | 陕西师范大学 | 2021-10-01 | — | — | CN | disclosed |