Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28630759 | 1.00 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2L3MBTL1ALDH1A1 | |
| SCHEMBL28642117 | 1.00 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2L3MBTL1ALDH1A1 | |
| SCHEMBL29086833 | 0.85 | L3MBTL1 (0.33) | L3MBTL1CA2 | |
| SCHEMBL28912789 | 0.80 | CA2 (0.37) | L3MBTL1CA2HCRTR1HCRTR2 | |
| SCHEMBL22309795 | 0.79 | CA2 (0.33) | L3MBTL1ALDH1A1CA2 | |
| SCHEMBL10965421 | 0.79 | L3MBTL1 (0.37) | L3MBTL1CA2HCRTR1HCRTR2 | |
| SCHEMBL18105793 | 0.78 | HCAR2 (0.45) | HCAR2KEAP1NFE2L2ALDH1A1KDM4E | |
| SCHEMBL4092900 | 0.77 | HCAR2 (0.39) | HCAR2KEAP1NFE2L2L3MBTL1ALDH1A1 | |
| SCHEMBL3989031 | 0.77 | HCAR2 (0.39) | HCAR2KEAP1NFE2L2L3MBTL1ALDH1A1 | |
| SCHEMBL3989029 | 0.77 | HCAR2 (0.39) | HCAR2KEAP1NFE2L2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490489-A | Monomethyl fumarate-carrier conjugates and methods of use thereof | 旗舰创业创新五公司 | 2021-10-08 | — | — | CN | disclosed |