Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29205228 | 0.85 | NR3C1 (0.60) | NR3C1PGR | |
| SCHEMBL28630821 | 0.75 | NR3C1 (0.73) | NR3C1PGR | |
| SCHEMBL3583710 | 0.74 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL3583714 | 0.74 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL8174904 | 0.73 | KCNH2 (0.60) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL3599365 | 0.67 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL3599363 | 0.67 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL10193341 | 0.66 | ROCK1 (0.55) | HPGDALDH1A1KDM4ESMN1; SMN2KCNH2 | |
| SCHEMBL6298998 | 0.65 | L3MBTL1 (0.47) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL149014 | 0.64 | KDM4E (0.54) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113382730-A | Selective glucocorticoid receptor modifiers for treatment of impaired skin wound healing | 阿克里斯生物医药有限公司 | 2021-09-10 | — | — | CN | disclosed |