Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.45 |
| ▸ | HTR3A | P46098 | 3/20 | 0.45 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21301013 | 0.82 | KCNJ1 (0.47) | MAPTKCNJ1ALDH1A1 | |
| SCHEMBL18724150 | 0.80 | KCNJ1 (0.43) | TDP1KCNJ1ALDH1A1HRH3 | |
| SCHEMBL23086941 | 0.79 | KCNJ1 (0.45) | MAPTKCNJ1ALDH1A1HRH3KMT2A | |
| SCHEMBL27858849 | 0.79 | MAPT (0.47) | TDP1MAPTKCNJ1ALDH1A1KMT2A | |
| SCHEMBL30712023 | 0.79 | MAPT (0.47) | TDP1MAPTKCNJ1ALDH1A1KMT2A | |
| SCHEMBL20148195 | 0.79 | KCNJ1 (0.39) | TDP1HRH4HTR3AKCNJ1HRH3 | |
| SCHEMBL23086572 | 0.77 | HRH3 (0.40) | ALDH1A1HRH3KMT2A | |
| SCHEMBL20148204 | 0.76 | MAP4K4 (0.40) | KCNJ1HRH3 | |
| SCHEMBL18724195 | 0.76 | HTR1A (0.42) | KCNJ1HRH3 | |
| SCHEMBL23086561 | 0.76 | ALDH1A1 (0.43) | MAPTKCNJ1ALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606908-B | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-117343063-A | Compounds as TRK inhibitors and/or RET inhibitors and uses thereof | 河南迈英诺医药科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-114075200-A | JAK inhibitor compounds for the treatment of severe pneumonia | 河南迈英诺医药科技有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-113563345-A | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-111606908-B | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-111606908-A | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |