SCHEMBL28630885

SCHEMBL28630885

NNC(=O)C1(OC(N)=O)CC(F)(F)C1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295039 0.83 NQO1 (0.32)
SCHEMBL29011864 0.78
SCHEMBL28625855 0.73
SCHEMBL28630287 0.72 ALOX15 (0.31)
SCHEMBL28634547 0.72
SCHEMBL27165875 0.68 DGAT1 (0.32) DGAT1
SCHEMBL21380493 0.67 DGAT1 (0.39) DGAT1
SCHEMBL23933140 0.64
SCHEMBL28687438 0.64 DGAT1 (0.36) DGAT1
SCHEMBL29221204 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113454077-A Amide derivatives for the treatment of HBV infection or HBV-induced diseases 爱尔兰詹森科学公司 2021-09-28 CN disclosed