Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | STK17B | O94768 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10318009 | 0.94 | KDM4E (0.46) | MEN1GAAKMT2ATDP1BRD4 | |
| SCHEMBL4597974 | 0.86 | CTSL (0.47) | CTSLCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16690784 | 0.86 | CTSL (0.47) | CTSLCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10319930 | 0.86 | CTSL (0.47) | CTSLCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25496760 | 0.85 | MEN1 (0.50) | MEN1GAAKMT2ATDP1BRD4 | |
| SCHEMBL3649756 | 0.85 | GAA (0.55) | MEN1GAAKMT2ATDP1BRD4 | |
| SCHEMBL25496756 | 0.85 | GAA (0.55) | MEN1GAAKMT2ATDP1BRD4 | |
| SCHEMBL6494079 | 0.84 | MEN1 (0.61) | MEN1GAAKMT2ATDP1DRD2 | |
| SCHEMBL6491658 | 0.84 | MEN1 (0.61) | MEN1GAAKMT2ATDP1DRD2 | |
| SCHEMBL6500581 | 0.84 | MEN1 (0.61) | MEN1GAAKMT2ATDP1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999479-B | Heteroaryl compounds useful as inhibitors of SUMO activating enzyme | 米伦纽姆医药公司 | 2021-07-16 | — | — | CN | disclosed |