Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16690784 | 1.00 | CTSL (0.47) | CTSLADRB3ADRB1ADRB2ADRA1D | |
| SCHEMBL10319930 | 1.00 | CTSL (0.47) | CTSLADRB3ADRB1ADRB2ADRA1D | |
| SCHEMBL10318009 | 0.87 | KDM4E (0.46) | CTSLCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16204368 | 0.87 | CTSL (0.47) | CTSLADRB3ADRB1ADRB2CYP1A2 | |
| SCHEMBL28630946 | 0.86 | MEN1 (0.50) | CTSLCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4597840 | 0.86 | CTSL (0.46) | CTSLCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4597442 | 0.86 | CTSL (0.46) | CTSLCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10319148 | 0.86 | CTSL (0.46) | CTSLCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12321338 | 0.85 | BCAT2 (0.43) | ADRB3ADRB1ADRB2 | |
| SCHEMBL2011968 | 0.85 | HIF1A (0.56) | ADRB3ADRB1ADRB2ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |