Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28642818 | 0.80 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1IDO1MAPTNPC1 | |
| SCHEMBL28195066 | 0.79 | SCN2A (0.43) | SMN1; SMN2ALDH1A1IDO1SCN2ANPBWR1 | |
| SCHEMBL28055593 | 0.79 | SCN2A (0.42) | SMN1; SMN2ALDH1A1IDO1SCN2ANPBWR1 | |
| SCHEMBL28641224 | 0.73 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1IDO1MAPTNPC1 | |
| SCHEMBL28646823 | 0.72 | ALDH1A1 (0.44) | ALDH1A1IDO1SCN2ATNKSKIF11 | |
| SCHEMBL28195685 | 0.69 | PDE2A (0.35) | SMN1; SMN2ALDH1A1PDE2AIDO1SCN2A | |
| SCHEMBL28195675 | 0.69 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1IDO1SCN2AMAPT | |
| SCHEMBL22475300 | 0.69 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1IDO1SCN2AMAPT | |
| SCHEMBL28195674 | 0.69 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1IDO1MAPTNPC1 | |
| SCHEMBL28195679 | 0.68 | IDO1 (0.35) | ALDH1A1IDO1SCN2AKIF11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107625766-B | Application of thiazole compound as antibacterial synergist | 上海医药工业研究院 | 2021-08-31 | — | — | CN | disclosed |