Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 4/20 | 0.42 |
| ▸ | GALR3 | O60755 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28195066 | 0.85 | SCN2A (0.43) | SCN2ASMN1; SMN2ALDH1A1IDO1MAPK13 | |
| SCHEMBL28195675 | 0.81 | ALDH1A1 (0.52) | SCN2ASMN1; SMN2ALDH1A1IDO1MAPK1 | |
| SCHEMBL28631508 | 0.79 | SMN1; SMN2 (0.36) | SCN2ASMN1; SMN2ALDH1A1IDO1MAPT | |
| SCHEMBL28195685 | 0.77 | PDE2A (0.35) | SCN2ASMN1; SMN2ALDH1A1IDO1LMNA | |
| SCHEMBL28195679 | 0.76 | IDO1 (0.35) | SCN2AALDH1A1IDO1MAPK14MAPT | |
| SCHEMBL31126418 | 0.75 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1IDO1MAPK13MAPK12 | |
| SCHEMBL31126426 | 0.75 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1IDO1MAPK13MAPK12 | |
| SCHEMBL28195676 | 0.73 | MAPT (0.45) | SCN2AALDH1A1MAPK14MAPTMEN1 | |
| SCHEMBL28646823 | 0.72 | ALDH1A1 (0.44) | SCN2AALDH1A1IDO1MAPK14MAPT | |
| SCHEMBL28636889 | 0.72 | TRPV1 (0.47) | SCN2AHTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107629022-A | A kind of Trimethoprim and its preparation method and purposes | 上海医药工业研究院 | 2018-01-26 | — | — | CN | disclosed |
| CN-106692569-A | Traditional Chinese medicine for treating cervical vertebra, lumbar vertebra and various kinds of arthritis | 商南县融汇城商贸有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-105381150-A | Traditional Chinese medicine composition for treating cervical spondylosis and lubar intervertebral disc protrusion | YANG CHUNFENG | 2016-03-09 | — | — | CN | disclosed |