SCHEMBL2863181

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2861529	0.85	MAPKAPK2 (0.53)	MAPKAPK2MAPK10ITKSIRT2SIRT1
	SCHEMBL2870292	0.82	MAPKAPK2 (0.48)	MAPKAPK2MAPK10ITKSIRT2SIRT1
	SCHEMBL2859875	0.82	MAPKAPK2 (0.46)	MAPKAPK2MAPK10ITKSIRT2SIRT1
	SCHEMBL2862999	0.81	MAPK10 (0.47)	MAPKAPK2MAPK10SIRT2SIRT1MAP2K4
	SCHEMBL2866652	0.78	TNIK (0.47)	MAPKAPK2MAPK10ITKSIRT2SIRT1
	SCHEMBL2862092	0.78	MAPK10 (0.49)	MAPKAPK2MAPK10ITKSIRT2SIRT1
	SCHEMBL2864582	0.76	CDK2 (0.47)	MAPKAPK2MAPK10ITKDYRK1AMAP2K4
	SCHEMBL4063951	0.75	ITK (0.42)	MAPKAPK2MAPK10ITKSIRT2SIRT1
	SCHEMBL2862938	0.74	MAPK10 (0.50)	MAPKAPK2MAPK10SIRT2SIRT1DYRK1A
	SCHEMBL4329381	0.74	MAPK10 (0.59)	MAPKAPK2MAPK10ITKSIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.