SCHEMBL2866652

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2862092	0.83	MAPK10 (0.49)	TNIKMAPKAPK2TRPV1MAPK10ITK
	SCHEMBL2861026	0.81	TNIK (0.49)	TNIKMAPKAPK2TRPV1MAPK10ACLY
	SCHEMBL4329381	0.78	MAPK10 (0.59)	MAPKAPK2MAPK10ITKNTRK1SIRT2
	SCHEMBL2861529	0.78	MAPKAPK2 (0.53)	MAPKAPK2MAPK10MAP2K4ITKSIRT2
	SCHEMBL2863181	0.78	MAPKAPK2 (0.48)	MAPKAPK2MAPK10MAP2K4ITKSIRT2
	SCHEMBL2866702	0.77	MAPK10 (0.44)	TNIKMAPKAPK2MAPK10ITKSIRT2
	SCHEMBL2862999	0.76	MAPK10 (0.47)	MAPKAPK2MAPK10ACLYMAP2K4SIRT2
	SCHEMBL4337651	0.76	MAPK10 (0.46)	MAPKAPK2MAPK10ITK
	SCHEMBL2862889	0.76	TNIK (0.48)	TNIKMAPKAPK2TRPV1MAPK10ACLY
	SCHEMBL2859875	0.75	MAPKAPK2 (0.46)	MAPKAPK2MAPK10ACLYMAP2K4ITK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.