SCHEMBL2861529

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2863181	0.85	MAPKAPK2 (0.48)	MAPKAPK2MAPK10APPSIRT2SIRT1
	SCHEMBL2870292	0.84	MAPKAPK2 (0.48)	MAPKAPK2MAPK10APPSIRT2SIRT1
	SCHEMBL2859875	0.82	MAPKAPK2 (0.46)	MAPKAPK2MAPK10SIRT2SIRT1ITK
	SCHEMBL2862999	0.81	MAPK10 (0.47)	MAPKAPK2MAPK10SIRT2SIRT1IKBKB
	SCHEMBL2862092	0.78	MAPK10 (0.49)	MAPKAPK2MAPK10SIRT2SIRT1ITK
	SCHEMBL2866652	0.78	TNIK (0.47)	MAPKAPK2MAPK10SIRT2SIRT1ITK
	SCHEMBL2864567	0.78	MAPKAPK2 (0.48)	MAPKAPK2MAPK10APPSIRT2SIRT1
	SCHEMBL22446034	0.77	MAP2K4 (0.59)	MAPK10PIM1PIM3PIM2DYRK1A
	SCHEMBL2864682	0.76	MAPKAPK2 (0.50)	MAPKAPK2MAPK10ITKIKBKBPIK3CD
	SCHEMBL4063951	0.75	ITK (0.42)	MAPKAPK2MAPK10SIRT2SIRT1ITK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.