Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NHERF1 | O14745 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GRK2 | P25098 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619945 | 0.88 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TDP1RECQLTP53 | |
| SCHEMBL28921679 | 0.85 | CYP1A2 (0.47) | ALDH1A1SMN1; SMN2POLBTDP1TP53 | |
| SCHEMBL11304141 | 0.84 | MAPT (0.57) | ALDH1A1SMN1; SMN2NCOR2TDP1TP53 | |
| SCHEMBL28626413 | 0.77 | GAA (0.65) | ALDH1A1POLBTDP1KDM4ETP53 | |
| SCHEMBL1939652 | 0.76 | KMT2A (0.73) | NHERF1ALDH1A1SMN1; SMN2POLBPPARG | |
| SCHEMBL12745804 | 0.74 | TSHR (0.60) | ALDH1A1SMN1; SMN2POLBTDP1KDM4E | |
| SCHEMBL7874122 | 0.74 | KMT2A (0.58) | ALDH1A1POLBPPARGNR2E3NCOR2 | |
| SCHEMBL11625375 | 0.73 | TP53 (0.58) | ALDH1A1SMN1; SMN2POLBNCOR2TDP1 | |
| SCHEMBL11627604 | 0.73 | HSD17B10 (0.59) | ALDH1A1NCOR2KMT2AMAPT | |
| SCHEMBL159731 | 0.72 | GLA (0.70) | SMN1; SMN2POLBNCOR2KMT2ACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336682-B | Synthesis method of sulfonyl carbamate | 苏州华道生物药业股份有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113336682-A | Synthesis method of sulfonyl carbamate | 苏州华道生物药业股份有限公司 | 2021-09-03 | — | — | CN | disclosed |