SCHEMBL28626413

SCHEMBL28626413

CCOC(=O)NCS(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.65
ALDH1A1 P00352 6/20 0.55
KDM4E B2RXH2 1/20 0.55
HPGD P15428 1/20 0.55
ALOX12 P18054 1/20 0.52
HTT P42858 1/20 0.48
TP53 P04637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
KAT6A Q92794 2/20 0.45
ALOX15 P16050 1/20 0.44
HIF1A Q16665 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
RAB9A P51151 1/20 0.44
CTSS P25774 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11304141 0.83 MAPT (0.57) GAAALDH1A1HPGDTP53TDP1
SCHEMBL28619945 0.80 ALDH1A1 (0.57) GAAALDH1A1HPGDALOX12TP53
SCHEMBL28921679 0.77 CYP1A2 (0.47) GAAALDH1A1HTTTP53TDP1
SCHEMBL28632298 0.77 NHERF1 (0.49) GAAALDH1A1KDM4ETP53TDP1
SCHEMBL13590662 0.75 ACACB (0.76) GAAALDH1A1CTSSPOLB
SCHEMBL4629467 0.74 GAA (0.61) GAAALDH1A1KDM4EHPGDHTT
SCHEMBL6270218 0.74 RAB9A (0.63) GAAALDH1A1KDM4EHPGDHTT
SCHEMBL14584231 0.73 ALDH1A1 (0.77) ALDH1A1HPGDALOX12TP53TDP1
SCHEMBL10420167 0.73 GAA (0.65) GAAALDH1A1KDM4EKMT2AMEN1
SCHEMBL2069060 0.73 GAA (0.74) GAAALDH1A1KDM4EHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113336682-B Synthesis method of sulfonyl carbamate 苏州华道生物药业股份有限公司 2021-11-02 CN disclosed
CN-113336682-A Synthesis method of sulfonyl carbamate 苏州华道生物药业股份有限公司 2021-09-03 CN disclosed