Butyramide

Butyramide

SCHEMBL28632307

CCCC(N)=O.Cc1cccc(NC(=O)O)c1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.54
CYP1A2 P05177 1/20 0.53
HDAC3 O15379 2/20 0.51
HDAC1 Q13547 2/20 0.51
HDAC2 Q92769 2/20 0.51
HDAC10 Q969S8 2/20 0.51
HDAC11 Q96DB2 2/20 0.51
HDAC8 Q9BY41 2/20 0.51
HDAC6 Q9UBN7 2/20 0.51
HDAC4 P56524 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC9 Q9UKV0 1/20 0.51
HDAC5 Q9UQL6 1/20 0.51
NPC1 O15118 1/20 0.51
POLB P06746 1/20 0.51
RAB9A P51151 1/20 0.51
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
NCOR2 Q9Y618 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyramide SCHEMBL28001896 0.84 CYP1A2 (0.50) CYP1A2HDAC3HDAC1HDAC2HDAC10
SCHEMBL30762995 0.83 HSD17B10 (0.74) HSD17B10CYP1A2POLBMEN1KMT2A
SCHEMBL692386 0.83 HSD17B10 (0.74) HSD17B10CYP1A2POLBMEN1KMT2A
Hydrochloric Acid SCHEMBL9576706 0.82 HSD17B10 (0.71) HSD17B10CYP1A2POLBMEN1KMT2A
SCHEMBL13994594 0.81 HDAC3 (0.69) HSD17B10CYP1A2HDAC3HDAC1HDAC2
Isobutyramide SCHEMBL28001869 0.80 HSD17B10 (0.59) HSD17B10CYP1A2POLBMEN1KMT2A
Benzene SCHEMBL15881255 0.79 HSD17B10 (0.67) HSD17B10CYP1A2POLBMEN1KMT2A
Toluene SCHEMBL28072686 0.78 CES2 (0.47) NPC1RAB9AMEN1KMT2AHPGD
Butyramide SCHEMBL28651096 0.78 CYP3A4 (0.56) HSD17B10NPC1RAB9AMEN1KMT2A
SCHEMBL12285798 0.78 HPGD (0.64) HSD17B10CYP1A2HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113229521-A Electronic atomized liquid composition and packaging container thereof 张家港外星人新材料科技有限公司 2021-08-10 CN disclosed