Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.61 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692386 | 1.00 | HSD17B10 (0.74) | HSD17B10KMT2AMEN1RXFP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9576706 | 0.98 | HSD17B10 (0.71) | HSD17B10KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL13681314 | 0.88 | CNR1 (0.65) | HSD17B10KMT2AMEN1RXFP1ALDH1A1 | |
| Isobutyramide SCHEMBL28001869 | 0.88 | HSD17B10 (0.59) | HSD17B10KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL23581565 | 0.88 | HSD17B10 (0.59) | HSD17B10KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL29703055 | 0.87 | SMN1; SMN2 (0.77) | HSD17B10KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL4416620 | 0.87 | SMN1; SMN2 (0.77) | HSD17B10KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL21567990 | 0.87 | HSD17B10 (0.74) | HSD17B10KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL11858223 | 0.86 | GPR35 (0.67) | HSD17B10KMT2AMEN1KCNK3KCNK9 | |
| SCHEMBL17400848 | 0.86 | GPR35 (0.74) | HSD17B10KMT2AMEN1RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568668-A2 | GPR6 INVERSE AGONISTS | MapLight Therapeutics, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024036288-A2 | GPR6 INVERSE AGONISTS | MAPLIGHT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |