SCHEMBL28632940

SCHEMBL28632940

CCOC(=O)C(c1ccccc1)C1CCCC1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.67
SLC6A3 Q01959 4/20 0.67
CYP3A4 P08684 2/20 0.67
TSHR P16473 2/20 0.67
LMNA P02545 2/20 0.67
CHRM2 P08172 1/20 0.67
HTR1A P08908 1/20 0.67
ADRA2A P08913 1/20 0.67
CHRM1 P11229 1/20 0.67
DRD1 P21728 1/20 0.67
ADRA1A P35348 1/20 0.67
OPRM1 P35372 1/20 0.67
DRD3 P35462 1/20 0.67
KCNH2 Q12809 1/20 0.67
CYP1A2 P05177 1/20 0.67
CYP2D6 P10635 1/20 0.67
SLC6A4 P31645 2/20 0.67
HTR1E P28566 2/20 0.55
S1PR3 Q99500 2/20 0.55
MEN1 O00255 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10955574 0.98 SLC6A2 (0.70) SLC6A2SLC6A3CYP3A4TSHRLMNA
SCHEMBL30771364 0.88 SLC6A2 (0.56) SLC6A2SLC6A3CYP3A4TSHRLMNA
SCHEMBL8193192 0.87 SLC6A2 (0.65) SLC6A2SLC6A3CYP3A4TSHRLMNA
SCHEMBL28622583 0.85 SLC6A2 (0.69) SLC6A2SLC6A3CYP3A4TSHRLMNA
SCHEMBL11932077 0.85 SLC6A3 (0.51) SLC6A2SLC6A3CYP3A4TSHRLMNA
SCHEMBL28627235 0.85 SLC6A3 (0.61) SLC6A2SLC6A3CYP3A4TSHRLMNA
SCHEMBL7489656 0.85 SLC6A2 (0.68) SLC6A2SLC6A3CYP3A4TSHRLMNA
SCHEMBL28622638 0.84 SLC6A3 (0.67) SLC6A2SLC6A3CYP3A4TSHRLMNA
SCHEMBL4206472 0.84 SLC6A3 (0.65) SLC6A2SLC6A3CYP3A4TSHRLMNA
SCHEMBL28637337 0.83 SLC6A2 (0.66) SLC6A2SLC6A3CYP3A4TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109457011-B Method for splitting alpha-cyclopentylphenylacetic acid enantiomer through stereoselective enzymatic hydrolysis 湖南理工学院 2021-09-07 CN disclosed