Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632940 | 0.87 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4CYP3A4CHRM2 | |
| SCHEMBL4537372 | 0.85 | SLC6A3 (0.64) | SLC6A2SLC6A3SLC6A4LMNATSHR | |
| SCHEMBL10955574 | 0.85 | SLC6A2 (0.70) | SLC6A2SLC6A3SLC6A4CYP3A4CHRM2 | |
| SCHEMBL13476487 | 0.84 | SLC6A3 (0.67) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL30771364 | 0.84 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4CYP3A4CHRM2 | |
| SCHEMBL4678502 | 0.82 | SLC6A3 (0.60) | SLC6A2SLC6A3SLC6A4LMNAOPRD1 | |
| SCHEMBL13114874 | 0.80 | CACNA2D1 (0.50) | SLC6A2SLC6A3SLC6A4LMNAOPRD1 | |
| SCHEMBL5080882 | 0.79 | SMYD3 (0.50) | CYP3A4LMNACYP1A2CYP2D6TSHR | |
| SCHEMBL21178229 | 0.78 | SLC6A2 (0.47) | SLC6A2SLC6A3SLC6A4OPRM1TSHR | |
| SCHEMBL6528518 | 0.77 | CACNA2D1 (0.48) | SLC6A2SLC6A3SLC6A4LMNAOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2025-11-13 | — | — | US | disclosed |
| EP-1047673-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2000-11-02 | — | — | EP | disclosed |
| US-6048856-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | NOVO NORDISK A/S (DK) | 2000-04-11 | — | — | US | disclosed |
| WO-1999031058-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | ROCK1, ROCK2, RHOA | SLC6A2 2961/4885SLC6A3 2540/4885SLC6A4 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.