Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628722 | 0.99 | MEN1 (0.35) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL28641710 | 0.82 | MEN1 (0.35) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL28628731 | 0.81 | ADORA2A (0.30) | ADORA2A | |
| SCHEMBL28622426 | 0.77 | TSHR (0.34) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL28638173 | 0.76 | MEN1 (0.36) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL28635812 | 0.76 | MEN1 (0.36) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL28629208 | 0.75 | HDAC1 (0.35) | KMT2AALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL28641717 | 0.73 | — | — | |
| SCHEMBL28636244 | 0.73 | HCAR3 (0.33) | HTTHCAR3 | |
| SCHEMBL28922708 | 0.71 | HPGD (0.40) | MEN1KMT2ATSHRHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232448-B | (E) -chloropropylketene/olefine aldehyde triazole compound and synthesis method thereof | 陕西师范大学 | 2021-09-21 | — | — | CN | disclosed |