Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 5/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28641609 | 0.91 | NPSR1 (0.39) | KCNJ6KCNJ5KCNJ3MAPTALDH1A1 | |
| SCHEMBL28621874 | 0.91 | TSHR (0.31) | NPSR1HCAR3TSHRKMT2A | |
| SCHEMBL28641716 | 0.88 | KCNJ6 (0.38) | KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL28923141 | 0.86 | ACP3 (0.34) | MAPTALDH1A1HCAR3 | |
| SCHEMBL28622426 | 0.77 | TSHR (0.34) | MAPTALDH1A1NPSR1TSHRKMT2A | |
| SCHEMBL28628722 | 0.76 | MEN1 (0.35) | KCNJ6KCNJ5KCNJ3MAPTALDH1A1 | |
| SCHEMBL28633072 | 0.75 | LMNA (0.33) | MAPTALDH1A1NPSR1HCAR3TSHR | |
| SCHEMBL28623306 | 0.71 | ALDH1A1 (0.41) | KCNJ6KCNJ5KCNJ3ALDH1A1TSHR | |
| SCHEMBL28621188 | 0.71 | ALDH1A1 (0.41) | KCNJ6KCNJ5KCNJ3ALDH1A1TSHR | |
| SCHEMBL28626339 | 0.69 | TSHR (0.40) | KCNJ6KCNJ5KCNJ3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232448-B | (E) -chloropropylketene/olefine aldehyde triazole compound and synthesis method thereof | 陕西师范大学 | 2021-09-21 | — | — | CN | disclosed |