Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28641681 | 0.90 | APP (0.66) | APPKMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL28641680 | 0.90 | APP (0.66) | APPKMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL28653005 | 0.89 | APP (0.64) | APPKMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL29966961 | 0.89 | APP (0.64) | APPKMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL28924850 | 0.86 | ACHE (0.68) | APPKMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL28639863 | 0.86 | APP (0.58) | APPKMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL28638131 | 0.86 | APP (0.58) | APPKMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL28639862 | 0.86 | APP (0.58) | APPKMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL28924931 | 0.86 | APP (0.84) | APPKMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL28639950 | 0.82 | ALDH1A1 (0.71) | APPKMT2AKDM4EMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461639-B | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-113461639-A | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2021-10-01 | — | — | CN | disclosed |