Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23970134 | 1.00 | EPHX2 (0.53) | EPHX2LMNASMN1; SMN2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL22163972 | 0.98 | EPHX2 (0.51) | EPHX2LMNASMN1; SMN2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL29411691 | 0.98 | EPHX2 (0.51) | EPHX2LMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL17352352 | 0.89 | EPHX2 (0.58) | EPHX2LMNASMN1; SMN2ALDH1A1GBA1 | |
| SCHEMBL17352418 | 0.81 | LMNA (0.55) | EPHX2LMNASMN1; SMN2ALDH1A1GGPS1 | |
| SCHEMBL14573044 | 0.77 | EPHX2 (0.53) | EPHX2LMNASMN1; SMN2ALDH1A1GGPS1 | |
| SCHEMBL1778693 | 0.77 | SMN1; SMN2 (0.61) | EPHX2LMNASMN1; SMN2ALDH1A1GGPS1 | |
| SCHEMBL17710359 | 0.72 | TSHR (0.87) | ALDH1A1TSHR | |
| SCHEMBL3010729 | 0.72 | TSHR (0.87) | ALDH1A1TSHR | |
| SCHEMBL21113627 | 0.72 | TSHR (0.87) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227036-B | Ethylenediamine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-04-11 | — | — | CN | disclosed |
| CN-113227036-A | Ethylenediamine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-08-06 | — | — | CN | disclosed |