Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.87 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.58 |
| ▸ | ADH1B | P00325 | 1/20 | 0.57 |
| ▸ | ADH1C | P00326 | 1/20 | 0.57 |
| ▸ | ADH1A | P07327 | 1/20 | 0.57 |
| ▸ | ADH4 | P08319 | 1/20 | 0.57 |
| ▸ | ADH7 | P40394 | 1/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519282 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL17710324 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL251953 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL10381778 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL17710359 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL17710352 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL25435977 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL7588265 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL21113627 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL11743896 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620906-B | Method for preparing ethylenediamine and ethanolamine derivatives by photocatalytic biomass polyalcohol | 中国科学院大连化学物理研究所 | 2023-05-19 | — | — | CN | claimed |
| US-20050089486-A1 | Self-tanning compositions and method of using the same | AMCOL INTERNATIONAL CORPORATION | 2005-04-28 | — | — | US | claimed |
| EP-4407067-A1 | PLATING BATH COMPOSITION FOR PLATING OF PRECIOUS METAL AND A METHOD FOR DEPOSITING A PRECIOUS METAL LAYER | Atotech Deutschland GmbH & Co. KG (DE) | 2024-07-31 | — | — | EP | disclosed |
| US-20120053092-A1 | Shale Hydration Inhibition Agents for Utilization in Water-based Drilling Fluids | ST. FRANCIS XAVIER UNIVERSITY (CA) | 2012-03-01 | — | — | US | disclosed |
| US-20100183688-A1 | Delivery System and Method of Manufacturing the Same | AMCOL INTERNATIONAL CORPORATION (US) | 2010-07-22 | — | — | US | disclosed |
| US-20050089486-A1 | Self-tanning compositions and method of using the same | AMCOL INTERNATIONAL CORPORATION | 2005-04-28 | — | — | US | disclosed |
| EP-0823427-B1 | Process for the preparation of high purity 1,3-dialkyl-2-imidazolidinone | MITSUI CHEMICALS INC (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6136984-A | Solid phase and combinatorial synthesis of substituted thiophenes and of arrays of substituted thiophenes | NOVO NORDISK A/S (DK) | 2000-10-24 | — | — | US | disclosed |
| EP-1021435-A1 | SOLID PHASE AND COMBINATORIAL SYNTHESIS OF SUBSTITUTED THIOPHENES AND OF ARRAYS OF SUBSTITUTED THIOPHENES | NOVO NORDISK A/S (DK) | 2000-07-26 | — | — | EP | disclosed |
| WO-2000023635-A1 | LIQUID COMPOUNDS FOR FORMATION OF MATERIALS CONTAINING ALKALINE EARTH METALS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-04-27 | — | — | WO | disclosed |
| US-5872260-A | High purity 1,3-dialkyl-2-imidazolidinone and preparation process of same | MITSUI CHEMICALS, INC. (JP) | 1999-02-16 | — | — | US | disclosed |
| US-5645822-A | DIHYDROXYACETONE, SECONDARY AMINE | SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0674504-B1 | METHOD AND APPARATUS FOR SUNLESS TANNING | SCHERING PLOUGH HEALTHCARE (US) | 1996-10-30 | — | — | EP | disclosed |
| EP-0220963-B1 | ADSORPTION OF GASES BY AMINE AND PHOSPHINE COMPLEXED MN(II) COMPOUNDS | UNIVERSITY OF CINCINNATI (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4767860-A | Preparation of N-substituted piperazinones | THE DOW CHEMICAL COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0264261-A2 | Preparation of N-substituted piperazinones | THE DOW CHEMICAL COMPANY (US) | 1988-04-20 | — | — | EP | disclosed |
| US-4713091-A | Adsorption of gases by amine and phosphine complexed Mn(II) and compounds | UNIVERSITY OF CINCINNATI (US) | 1987-12-15 | — | — | US | disclosed |
| US-4668255-A | Adsorption of gases by amine complexed Mn (II) | UNIVERSITY OF CINCINNATI (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0220963-A2 | Adsorption of gases by amine and phosphine complexed Mn(II) compounds | UNIVERSITY OF CINCINNATI (US) | 1987-05-06 | — | — | EP | disclosed |
| US-4048324-A | COPPER SALT OR HYDROXIDE, ALIPHATIC AMINE OR POLYAMINE | KOHN ARMAND | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053092-A1 | Shale Hydration Inhibition Agents for Utilization in Water-based Drilling Fluids | AQP1, AQP3, SLC26A4 | TSHR 2756/4885ALDH1A1 2904/4885EPHX1 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.