Methylene Chloride

Methylene Chloride

SCHEMBL28633238

CC(C)(C)OC(C)(C)C.ClCCl

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL5481886 0.96 ALDH1A1 (0.31) ALDH1A1TSHRTDP1
Ethyl Chloride SCHEMBL11023458 0.88 TSHR (0.31) ALDH1A1TSHRTDP1
1,2-Dichloroethane SCHEMBL15156482 0.85 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL8913 0.82
SCHEMBL28365346 0.82 ALDH1A1 (0.46) ALDH1A1TSHRTDP1
Propane SCHEMBL1683354 0.78 TSHR (0.36) ALDH1A1TSHRTDP1
Ethane SCHEMBL353672 0.77 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
Potassium SCHEMBL183183 0.77 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
Water SCHEMBL8067978 0.77 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
SCHEMBL30933076 0.77 ALDH1A1 (0.42) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113423685-A Prodrug modulators of integrated stress pathways 卡里科生命科学有限责任公司 2021-09-21 CN disclosed