Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL28633238 | 0.96 | ALDH1A1 (0.33) | ALDH1A1TSHRTDP1 | |
| 1,2-Dichloroethane SCHEMBL15156482 | 0.89 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| Ethyl Chloride SCHEMBL11023458 | 0.85 | TSHR (0.31) | ALDH1A1TSHRTDP1 | |
| Methane SCHEMBL30637 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1 | |
| Methane SCHEMBL759221 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1 | |
| SCHEMBL28041774 | 0.79 | TSHR (0.37) | ALDH1A1TSHRTDP1 | |
| SCHEMBL8913 | 0.78 | — | — | |
| SCHEMBL28365346 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1 | |
| Methyl Alcohol SCHEMBL1172804 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1 | |
| Propane SCHEMBL1683354 | 0.75 | TSHR (0.36) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119378-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2022-04-21 | — | — | US | disclosed |
| US-20210388020-A1 | PROCESS FOR THE PREPARATION OF 3ALPHA-HYDROXY-5ALPHA-PREGNAN-20-0NE (BREXANOLONE) | INDUSTRIALE CHIMICA S.R.L. (IT) | 2021-12-16 | — | — | US | disclosed |
| CN-104927876-B | Polymerizable compounds and their use in liquid crystal displays | 默克专利股份有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-112251242-A | Liquid-crystalline medium and liquid-crystal display | 默克专利股份有限公司 | 2021-01-22 | — | — | CN | disclosed |
| WO-2020160100-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| EP-3323872-B1 | COMPOUNDS FOR HOMOTROPIC ALIGNMENT OF LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2020-04-15 | — | — | EP | disclosed |
| US-9556215-B2 | Synthetic pentasaccharides having short half-life and high activity | CARBOMIMETICS (FR) | 2017-01-31 | — | — | US | disclosed |
| EP-2721044-B1 | SYNTHETIC PENTASACCHARIDES HAVING SHORT HALF-LIFE AND HIGH ACTIVITY | CARBOMIMETICS (FR) | 2015-11-18 | — | — | EP | disclosed |
| US-20140315814-A1 | SYNTHETIC PENTASACCHARIDES HAVING SHORT HALF-LIFE AND HIGH ACTIVITY | CARBOMIMETICS (FR) | 2014-10-23 | — | — | US | disclosed |
| EP-2721044-A1 | SYNTHETIC PENTASACCHARIDES HAVING SHORT HALF-LIFE AND HIGH ACTIVITY | Carbomimetics (FR) | 2014-04-23 | — | — | EP | disclosed |
| US-20070275985-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-29 | — | — | US | disclosed |
| US-20060281767-A1 | Triazoloypyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-12-14 | — | — | US | disclosed |
| US-6914059-B2 | Benzoxazine and benzothiazine derivatives and the use thereof in medicaments | SCHERING AG (DE) | 2005-07-05 | — | — | US | disclosed |
| US-20050119481-A1 | Novel amidine derivatives and the use of the same in pharmaceuticals | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-02 | — | — | US | disclosed |
| US-20040006075-A1 | Benzoxazine and benzothiazine derivatives and the use thereof in medicaments | SCHERING AG (DE) | 2004-01-08 | — | — | US | disclosed |
| EP-0750619-B1 | HETERO-ANNULATED INDAZOLES | NOVUSPHARMA SPA (IT) | 2001-05-30 | — | — | EP | disclosed |
| US-5807899-A | Triphenylethylenes, process for their production, pharmaceutical preparations that contain these triphenylethylenes as well as their use for the production of pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| US-5596097-A | ANTITUMOR AGENTS | THE UNIVERSITY OF VERMONT (US) | 1997-01-21 | — | — | US | disclosed |
| EP-0750619-A1 | HETERO-ANNULATED INDAZOLES | BOEHRINGER MANNHEIM ITALIA S.p.A. (IT) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995024407-A1 | HETERO-ANNULATED INDAZOLES | BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) | 1995-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006075-A1 | Benzoxazine and benzothiazine derivatives and the use thereof in medicaments | CYP4Z1, XDH, CYP3A5 | ALDH1A1 998/4885TSHR 3283/4885TDP1 1696/4885 |
| US-20050119481-A1 | Novel amidine derivatives and the use of the same in pharmaceuticals | NGLY1, OAT, SLC10A1 | ALDH1A1 4216/4885TSHR 1063/4885TDP1 2412/4885 |
| US-20060281767-A1 | Triazoloypyrimidines | DPYD, TYMP, P2RX5 | ALDH1A1 731/4885TSHR 906/4885TDP1 96/4885 |
| US-20070275985-A1 | Triazolopyrimidines | DPYD, QDPR, P2RX5 | ALDH1A1 395/4885TSHR 961/4885TDP1 175/4885 |
| US-20140315814-A1 | SYNTHETIC PENTASACCHARIDES HAVING SHORT HALF-LIFE AND HIGH ACTIVITY | TFPI, F11, F10 | ALDH1A1 2067/4885TSHR 2919/4885TDP1 4625/4885 |
| US-20220119378-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | ALDH1A1 2571/4885TSHR 4351/4885TDP1 725/4885 |
| US-20210388020-A1 | PROCESS FOR THE PREPARATION OF 3ALPHA-HYDROXY-5ALPHA-PREGNAN-20-0NE (BREXANOLONE) | CYP17A1, HSD17B7, CYP21A2 | ALDH1A1 751/4885TSHR 291/4885TDP1 3052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.